We discuss the latest in health news. This week, we bring you on a tour of the eating experience–from the tongue to the nose and we end with the people who eat with us. Join us and learn how a “dulled” tongue drives sugar intake, how smells trigger the incinerator within you, and how a mirror makes you eat more. We speak to Celine Riera, Assistant Professor in Cedars-Sinai Medical Center; Robin Dando, Assistant Professor in Department of Food Science, Cornell University; Suzanne Higgs, Professor in Psychobiology of Appetite, University of Birmingham; and Sarah-Jeanne Salvy, Associate Professor at University of Alabama.
Tags: The Bigger Picture, Health and Living, eating, diet, social facilitation, social modeling, obesity, fats, sugar, sensory, Cornell, parenting, smells, taste, health news digest, Gymnema sylvestre, Cedars-Sinai, Healthcare, Pharma, Biotech, Health
Sci. Signal. 25 Jul 2017: Olfactory control of metabolism
The scent of food is important for the perception of flavor and triggers physiological responses that prepare the body for a meal, such as increased secretion of saliva and gastric acid. Riera et al. report that the sense of smell also affects metabolism. OMPDTR mice, in which olfactory sensory neurons (OSNs) were selectively ablated by treating young animals with diphtheria toxin, did not gain as much weight as did wild-type mice when fed a high-fat diet (HFD)….
Our sense of smell is key to the enjoyment of food, so it may be no surprise that in experiments at the University of California, Berkeley, obese mice who lost their sense of smell also lost weight….
By MARY BROPHY MARCUS CBS NEWS July 6, 2017, 5:53 PM
Would you be willing to give up the smell of fresh-baked chocolate chip cookies or a pizza right out of the oven if it meant slimming down?
A new study showed that mice that lost their sense of smell didn’t gain weight even when they ate the same high-fat diet as mice that could smell and did gain weight.
The mice that retained their sense of smell packed on twice their normal weight while the smell-deficient mice didn’t gain at all, scientists from the University of California, Berkeley, reported in the journal Cell Metabolism.
A group of mice whose olfactory neurons had been genetically altered to take away their sense of smell were also compared with another group of mice whose sense of smell had been enhanced. The “super-smellers” gained even more weight.
Does my sense of smell make me look fat? In mice, the answer seems to be yes
A new study finds that mice with little or no ability to detect odors may have a key advantage to weight management. (July 6, 2017)
Welcome to Harshita Chodavarapu! Harshita obtained her PhD from Louisiana state University in 2017 under the supervision of Eric Lazartigues. At Cedars, Harshita brings her great expertise in pancreatic beta cells and molecular mechanisms of diabetes and will tackle important questions related to beta cell-neuron communication in metabolic health. We are thrilled to have Harshita in Los Angeles and wish her the best in her future work and new Californian life!
Betty Chang, Research Associate & Lab Manager
M.S., Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University-Taipei, 2014
B.S, Biological Sciences, University of California- Riverside, 2011
Research Assistant- Palo Alto Veterans Institute for Research, Department of Neurology and Neurological Sciences, Wyss-Coray Lab, Stanford University (05/2015-3/2017)
Graduate work- National Yang-Ming University, Department of Biomedical Imaging and Radiological Studies, Jeng-Jong Hwang Lab (09/2012-07/2014)
Starting in 2012, the American Diabetes Association established the Pathway to Stop Diabetes initiative, a $1.6 million grant (paid over five years) to support the research of young up-and-coming scientists who are committed to working on innovative projects in diabetes…
Scientists have found a way to beat back the hands of time and fight the ravages of old age, at least in mice. A new study finds that mice bred without a specific pain sensor, or receptor, live longer and are less likely to develop diseases such as diabetes in old age. What’s more, exposure to a molecule found in chili peppers and other spicy foods may confer the same benefits as losing this pain receptor—meaning that humans could potentially benefit, too…