Sci. Signal. 25 Jul 2017: Olfactory control of metabolism
The scent of food is important for the perception of flavor and triggers physiological responses that prepare the body for a meal, such as increased secretion of saliva and gastric acid. Riera et al. report that the sense of smell also affects metabolism. OMPDTR mice, in which olfactory sensory neurons (OSNs) were selectively ablated by treating young animals with diphtheria toxin, did not gain as much weight as did wild-type mice when fed a high-fat diet (HFD)….